What is Chancroid?

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Dr Thanushree, has her MBBS from Kanachur Institute of Medical Sciences, Mangalore
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Updated on 26 February, 2025
- Article was updated as part of our commitment to diversity, equity, and inclusion.
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Chancroid, a sexually transmitted infection (STI) caused by the bacterium Haemophilus ducreyi, poses a significant health concern globally. Though less common compared to other STIs like gonorrhea or chlamydia, its impact on individuals’ health and wellbeing can be profound. In this comprehensive guide, we delve into the intricacies of chancroid, covering its epidemiology, etiology, clinical manifestations, diagnostic approaches, treatment modalities, prevention strategies, and frequently asked questions (FAQs).
Epidemiology
Chancroid remains prevalent in regions with limited access to healthcare and resources, particularly in low- and middle-income countries. The incidence of chancroid has significantly decreased in industrialized nations due to improved hygiene practices, access to healthcare, and the widespread use of condoms. However, it continues to be a significant public health issue in parts of Africa, Southeast Asia, and the Caribbean.
Etiology
Chancroid is primarily transmitted through sexual contact with an infected individual. The bacterium Haemophilus ducreyi enters the body through microtears in the skin or mucous membranes, establishing infection in the genital region. Factors such as multiple sexual partners, unprotected intercourse, and concurrent STIs increase the risk of chancroid transmission.
Clinical Manifestations
The hallmark symptom of chancroid is the development of painful genital ulcers. These ulcers typically appear within a week after exposure to the bacteria and are characterized by their tender, ragged edges and gray or yellowish exudate. In men, the ulcers commonly occur on the foreskin, glans penis, or shaft, while in women, they are often found on the labia minora, labia majora, or vaginal walls. Additionally, individuals may experience tender and swollen inguinal lymph nodes, known as buboes, which can progress to abscess formation if left untreated.
Diagnostic Approaches
Diagnosing chancroid requires a thorough clinical evaluation, including a detailed medical history and physical examination. Healthcare providers may visually inspect the genital region for the presence of ulcers and palpate inguinal lymph nodes for tenderness or enlargement. Laboratory tests, such as Gram stain and culture of ulcer exudate, are often performed to confirm the diagnosis and identify the causative agent, Haemophilus ducreyi.
Treatment Modalities
Antibiotic therapy is the cornerstone of chancroid treatment, aiming to eradicate the bacterial infection and alleviate symptoms. Commonly prescribed antibiotics include azithromycin, ceftriaxone, or erythromycin, administered either orally or through intramuscular injection. In cases of large or painful ulcers, incision and drainage may be necessary to promote healing and reduce discomfort. It is imperative for individuals diagnosed with chancroid to complete the full course of antibiotics as prescribed by their healthcare provider to ensure successful treatment and prevent recurrence.
Prevention Strategies
Preventing chancroid necessitates a multifaceted approach focused on sexual health education, promotion of safer sexual practices, and access to comprehensive healthcare services. Key prevention strategies include:
- Condom Use: Consistent and correct use of condoms during sexual intercourse can significantly reduce the risk of chancroid transmission.
- Limiting Sexual Partners: Minimizing the number of sexual partners and practicing mutual monogamy can lower the likelihood of exposure to STIs, including chancroid.
- Regular Screening: Routine STI screening, including testing for chancroid, enables early detection and prompt treatment, reducing the risk of complications and transmission.
- Partner Notification and Treatment: Individuals diagnosed with chancroid should inform their sexual partners about their infection and encourage them to seek medical evaluation and treatment to prevent further spread.
Chancroid, though relatively rare in comparison to other sexually transmitted infections, remains a significant health concern in certain regions, particularly in developing countries. Its potential complications and association with increased HIV transmission emphasize the importance of timely diagnosis and treatment. Understanding its symptoms, risk factors, and preventive measures is crucial for both individuals and healthcare providers in combating its spread and mitigating its impact on public health. By fostering awareness, promoting safe sexual practices, and ensuring access to appropriate healthcare services, we can strive towards reducing the burden of chancroid and enhancing overall sexual health outcomes.
